MCIC Computational Biology Lab (MCBL)¶

Our goal¶

Our mission is to build core support and intellectual leadership in the area of bioinformatics to support research at the OARDC, by providing an engaging work environment, space, infrastructure and training for performing research involving biological data analysis.

We aspire for the MCBL to become the place to be for learning and performing bioinformatics research at the OARDC, the place where ideas are discussed and exchanged, students and users learn from each other and get help and support from our experienced staff when needed, and we as a community move our bioinformatics knowledge forward.

We specialize in working with High-throughput Sequencing (HTS) data and providing training in reproducible science using modern tools.

We are happy to help you to carry out your own analysis. This will include helping with experimental design, discussing the most effective way to carry out your data analysis, providing the computational infrastructure (software, scripts and computers), interpreting results, and answering questions you might come across along the way. We can also process and analyze HTS data for you, using either standardized or custom pipelines.

MCBL services¶

Data analysis	Contacts
Processing, analyzing, and interpreting HTS data WGS, RADseq/GBS, RNAseq, metagenomics, microbiomics, … Quality control Genotyping Genome assembly and annotation Differential expression analyses Population genetic and genomic analyses GWAS, (e)QTL analyses	Jelmer Poelstra

Workshops & training Contacts

UNIX command line and bash scripting
Running analyses at the Ohio Supercomputer Center (OSC)
Running analyses in the cloud
R - general, bioinformatics, R markdown, dashboarding
Python - general, bioinformatics
Reproducible compute environments with containers and conda
Reproducible analysis pipelines with Snakemake
Version control with git and Github
Data management and deposition in public repositories

Jelmer Poelstra

High-throughput Sequencing services	Contacts
Illumina Miseq	Tea Meulia (director) Fiorella Cisneros Carter